Effects of solutions of 0.5% bupivacaine, containing different concentrations of dextrose (0%, 0.5%, 0.8%, 1%, 3%, 5%, 8%) were studied after intrathecal injection in seven (Group A-Group G) groups of 15 patients.
@ES The results are summarized as follows :
@EN 1. The mean specific gravity of solutions was 1.0065, 1.0087, 1.0092, 1.0094, 1.0152, 1.0198 and 1.0314 (Group A-Group G). These values are isobaric (Group A, B), hyperbaric (Group E, F, G), and slightly hyperbaric (Group C, D) compared to
cerebrospinal fluid at 25℃.
2. The mean maximum level of sensory block was increased according to the increment of specific gravity of the solutions. But no significant differences between Group A and B, Group C and D, Group E, F, and G.
3. The mean time of sensory block to T11 was decreased according to the increment of specific gravity of the solutions.
4. The mean time to the expected level (T4) of sensory block at given dosage of each solution was 25.7, 18.4, 9.7 minutes(Group E, F, G, respectively).
5. Complete motor block of the legs was rapid according to the increment of specific gravity of the solutions.
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